We develop protein therapeutics to address unmet medical needs primarily in infectious diseases. These proteins aim to directly interfere in disease progression or augment essential immune system activities. To do this, we design proteins that bind specific sites on other proteins and bind with rates that will achieve our objectives. We then produce these proteins in recombinant expression systems, perform biophysical and biochemical analyses and ultimately, in vitro cellular and in vivo experiments to evaluate a protein's therapeutic potential.
A number of our prior undergraduate researchers have won NSF GRFP fellowships for graduate school, and many have gone on to graduate school, medical school, MD/PhD programs and industry position in the biotech. pharmaceutical field.