Andrea C Gore
Job Title
Research Interests

Work in the Gore Laboratory focuses on effects of endocrine-disrupting chemicals (EDCs) on the neuroendocrine control of reproduction and behavior. Current research in a rat model seeks to understand how prenatal exposure to environmental endocrine disruptors (EDCs) changes the developing brain by inducing molecular and cellular changes to neurons in the hypothalamus and other brain regions. Beyond this work on direct effects of EDCs on developing individuals, we seek to understand how EDC exposures can lead to multigenerational behavioral changes through epigenetic actions on the germline and gametes, the precursors to ova and sperm, which become the next generation. Our team uses a variety of techniques, including behavioral, physiological, neuroanatomical, immunohistochemical, and molecular (gene expression, epigenetic profiling, DNA methylation, RNAscope) approaches.